brown #
= weekly rock chart peak
blue #
= pop chart peak
| 1 | Bette Davis Eyes | 12 | 1 | May 1981 |  |
| Kim Carnes |
| 2 | Endless Love | 1 | Aug 1981 | |
| Diana Ross & Lionel Richie |
| 3 | Physical | 1 | Nov 1981 | |
| Olivia Newton-John |
| 4 | (Just Like) Starting Over | 1 | 1 | Dec 1980 | |
| John Lennon |
| 5 | The Tide Is High | 5 | 1 | Jan 1981 | |
| Blondie |
| 6 | Private Eyes | 1 | Oct 1981 | |
| Daryl Hall And John Oates |
| 7 | Waiting For A Girl Like You | 1 | 1 | Nov 1981 | |
| Foreigner |
| 8 | Celebration | 1 | Feb 1981 | |
| Kool And The Gang |
| 9 | Who's Crying Now | 2 | 1 | Sep 1981 | |
| Journey |
| 10 | Arthur's Theme (Best That You Can Do) | 1 | Oct 1981 | |
| Christopher Cross |
| 11 | Queen Of Hearts | 2 | Aug 1981 | |
| Juice Newton |
| 12 | Being With You | 1 | May 1981 | |
| Smokey Robinson |
| 13 | Woman | 1 | 1 | Mar 1981 | |
| John Lennon |
| 14 | Believe It Or Not (Theme From Greatest American Hero) | 1 | Jul 1981 | |
| Joey Scarbury |
| 15 | Morning Train (Nine To Five) | 1 | Apr 1981 | |
| Sheena Easton |
| 16 | Keep On Loving You | 1 | 2 | Feb 1981 | |
| REO Speedwagon |
| 17 | The One That You Love | 1 | Jul 1981 | |
| Air Supply |
| 18 | Just The Two Of Us | 1 | Apr 1981 | |
| Grover Washington, Jr. with Bill Withers |
| 19 | Kiss On My List | 1 | Apr 1981 | |
| Daryl Hall And John Oates |
| 20 | Every Woman In The World | 2 | Jan 1981 | |
| Air Supply |
| 21 | Passion | 2 | 2 | Jan 1981 | |
| Rod Stewart |
| 22 | I Love A Rainy Night | 2 | Feb 1981 | |
| Eddie Rabbitt |
| 23 | Slow Hand | 1 | Aug 1981 | |
| Pointer Sisters |
| 24 | The Best Of Times | 4 | 1 | Mar 1981 | |
| Styx |
| 25 | 9 To 5 | 1 | Feb 1981 | |
| Dolly Parton |