brown #
= weekly rock chart peak
blue #
= pop chart peak
| 1 | What A Girl Wants | 1 | 12-25-99 |  |
| Christina Aguilera |
| 2 | All The Small Things | 1 | 1 | 1-01-00 | |
| Blink 182 |
| 1-08-00 |
| What A Girl Wants by Christina Aguilera returns to number one |
| 3 | Show Me The Meaning Of Being Lonely | 1 | 1-15-00 | |
| Backstreet Boys |
| 4 | Amazed | 1 | 2-05-00 | |
| Lonestar |
| 5 | Bye, Bye, Bye | 1 | 2-19-00 | |
| 'NSYNC |
| 6 | Maria, Maria | 1 | 3-04-00 | |
| Santana Featuring The Product G&B |
| 7 | Say My Name | 1 | 3-11-00 | |
| Destiny's Child |
| 8 | It Feels So Good | 22 | 1 | 3-18-00 | |
| Sonique |
| 9 | Thong Song | 1 | 3-25-00 | |
| Sisqo |
| 10 | I Try | 1 | 4-08-00 | |
| Macy Gray |
| 11 | There You Go | 1 | 4-15-00 | |
| Pink |
| 12 | I Wanna Know | 1 | 4-22-00 | |
| Joe |
| 13 | Oops!... I Did It Again | 1 | 4-29-00 | |
| Britney Spears |
| 14 | The Real Slim Shady | 6 | 1 | 5-13-00 | |
| Eminem |
| 15 | Try Again | 1 | 5-20-00 | |
| Aaliyah |
| 16 | It's Gonna Be Me | 1 | 5-27-00 | |
| 'NSYNC |
| 17 | Swear It Again | 1 | 6-03-00 | |
| Westlife |
| 18 | Higher | 1 | 1 | 6-10-00 | |
| Creed |
| 19 | Be With You (Solo Me Importas Tu) | 1 | 6-17-00 | |
| Enrique Iglesias |
| 20 | Bent | 16 | 1 | 7-01-00 | |
| Matchbox 20 |
| 21 | Jumpin, Jumpin | 1 | 7-08-00 | |
| Destiny's Child |
| 22 | Who Let The Dogs Out | 1 | 7-22-00 | |
| Baha Men |
| 23 | Doesn't Really Matter | 1 | 7-29-00 | |
| Janet Jackson |
| 24 | Purest Of Pain (A Puro Dolor) | 1 | 8-12-00 | |
| Son By Four |
| 25 | Come On Over Baby (All I Want Is You) | 1 | 8-19-00 | |
| Christina Aguilera |
| 26 | Music | 1 | 9-02-00 | |
| Madonna |
| 27 | Give Me Just One Night (Una Noche) | 1 | 9-16-00 | |
| 98 Degrees |
| 28 | Kryptonite | 1 | 1 | 9-23-00 | |
| 3 Doors Down |
| 29 | With Arms Wide Open | 1 | 1 | 9-30-00 | |
| Creed |
| 30 | Shape Of My Heart | 1 | 10-21-00 | |
| Backstreet Boys |
| 31 | This I Promise You | 1 | 10-28-00 | |
| 'NSYNC |
| 32 | Case Of The Ex (Whatcha Gonna Do) | 1 | 11-04-00 | |
| Mya |
| 33 | Independent Women Part 1 | 1 | 11-11-00 | |
| Destiny's Child |
| 34 | It Wasn't Me | 1 | 12-02-00 | |
| Shaggy Featuring Ricardo RikRok Ducent |
| 35 | Stan | 6 | 1 | 12-23-00 | |
| Eminem Featuring Dido |