brown #
= weekly rock chart peak
blue #
= pop chart peak
| 26 | What's Left Of Me | 3 | May 2006 |  |
| Nick Lachey |
| 27 | Bad Day | 1 | May 2006 | |
| Daniel Powter |
| 28 | London Bridge | 1 | Aug 2006 | |
| Fergie |
| 29 | Where'd You Go | 1 | May 2006 | |
| Fort Minor Featuring Holly Brook & Jonah Matranga |
| 30 | (When You Gonna) Give It Up To Me | 1 | Aug 2006 | |
| Sean Paul Featuring Keyshia Cole |
| 31 | Walk Away | 3 | Feb 2006 | |
| Kelly Clarkson |
| 32 | Too Little Too Late | 2 | Sep 2006 | |
| JoJo |
| 33 | Chasing Cars | 2 | 2 | Oct 2006 | |
| Snow Patrol |
| 34 | Move Along | 11 | 2 | May 2006 | |
| The All-American Rejects |
| 35 | Call Me When You're Sober | 2 | 3 | Oct 2006 | |
| Evanescence |
| 36 | Savin' Me | 15 | 3 | May 2006 | |
| Nickelback |
| 37 | Hurt | 3 | Dec 2006 | |
| Christina Aguilera |
| 38 | Grillz | 2 | Feb 2006 | |
| Nelly Featuring Paul Wall, Ali & Gipp |
| 39 | Ain't No Other Man | 3 | Jul 2006 | |
| Christina Aguilera |
| 40 | If It's Lovin' That You Want | 4 | Jan 2006 | |
| Rihanna |
| 41 | Gallery | 3 | Oct 2006 | |
| Mario Vazquez Featuring Baby Bash |
| 42 | I'm N Luv (Wit A Stripper) | 3 | Mar 2006 | |
| T-Pain Featuring Mike Jones |
| 43 | Walk Away (Remember Me) | 5 | Dec 2006 | |
| Paula DeAnda Featuring The Dey |
| 44 | Crazy | 4 | 5 | Jul 2006 | |
| Gnarls Barkley |
| 45 | It Ends Tonight | 4 | Dec 2006 | |
| The All-American Rejects |
| 46 | Do It To It | 3 | Aug 2006 | |
| Cherish Featuring Sean Paul Of The YoungBloodZ |
| 47 | Everytime We Touch | 5 | Mar 2006 | |
| Cascada |
| 48 | I'm Sprung | 5 | Jan 2006 | |
| T-Pain |
| 49 | U And Dat | 4 | Sep 2006 | |
| E-40 Featuring T-Pain & Kandi Girl |
| 50 | Sexy Love | 4 | Sep 2006 | |
| Ne-Yo |