blue #
= weekly pop chart peak
| 1 | I'm Sprung | 5 | Jan 2006 |  |
| 2 | I'm N Luv (Wit A Stripper) | 3 | Mar 2006 | |
| T-Pain Featuring Mike Jones |
| 3 | U And Dat | 4 | Sep 2006 | |
| E-40 Featuring T-Pain & Kandi Girl |
| 4 | Outta My System | 25 | May 2007 | |
| Bow Wow Featuring T-Pain & Johnta Austin |
| 5 | Buy U A Drank (Shawty Snappin') | 4 | May 2007 | |
| T-Pain Featuring Yung Joc |
| 6 | I'm A Flirt | 16 | May 2007 | |
| R. Kelly Featuring T.I. & T-Pain |
| 7 | Bartender | 4 | Sep 2007 | |
| T-Pain Featuring Akon |
| 8 | Shawty | 20 | Sep 2007 | |
| Plies Featuring T-Pain |
| 9 | Cyclone | 10 | Oct 2007 | |
| Baby Bash Featuring T-Pain |
| 10 | I'm So Hood | Nov 2007 | |
| DJ Khaled Featuring T-Pain, Trick Daddy, Rick Ross And Plies |
| 11 | Baby Don't Go | 24 | Nov 2007 | |
| Fabolous Featuring T-Pain & Jermaine Dupri |
| 12 | Kiss Kiss | 2 | Nov 2007 | |
| Chris Brown Featuring T-Pain |
| 13 | Good Life | 18 | Dec 2007 | |
| Kanye West Featuring T-Pain |
| 14 | Low | 1 | Jan 2008 | |
| Flo Rida Featuring T-Pain |
| 15 | Who The Fxxk Is That | Mar 2008 | |
| Dolla Featuring T-Pain And Tay Dizm |
| 16 | Shawty Get Loose | Apr 2008 | |
| Lil Mama Featuring Chris Brown And T-Pain |
| 17 | Supa Sexxy | Apr 2008 | |
| Charlie Wilson Featuring T-Pain |
| 18 | The Boss | May 2008 | |
| Rick Ross Featuring T-Pain |
| 19 | Migrate | May 2008 | |
| Mariah Carey Featuring T-Pain |
| 20 | She Got It | 29 | Jun 2008 | |
| 2 Pistols Featuring T-Pain And Tay Dizm |
| 21 | Can't Believe It | 25 | Sep 2008 | |
| T-Pain Featuring Lil Wayne |
| 22 | Go Hard | Oct 2008 | |
| DJ Khaled Featuring Kanye West & T-Pain |
| 23 | Got Money | 16 | Oct 2008 | |
| Lil Wayne Featuring T-Pain |
| 24 | Go Girl | Oct 2008 | |
| Ciara Featuring T-Pain |
| 25 | Freeze | Nov 2008 | |
| T-Pain Featuring Chris Brown |
| 26 | Chopped N Skrewed | Dec 2008 | |
| T-Pain Featuring Ludacris |
| 27 | One More Drink | 22 | Jan 2009 | |
| Ludacris Co-Starring T-Pain |
| 28 | Hustler's Anthem 09 | Feb 2009 | |
| Busta Rhymes Featuring T-Pain |
| 29 | All The Above | Mar 2009 | |
| Maino Featuring T-Pain |
| 30 | Maybach Music 2 | May 2009 | |
| Rick Ross Featuring Kanye West, T-Pain & Lil Wayne |
| 31 | Blame It | 3 | May 2009 | |
| Jamie Foxx Featuring T-Pain |
| 32 | I'm On A Boat | Jun 2009 | |
| The Lonely Island Featuring T-Pain |
| 33 | Download | Jul 2009 | |
| Lil Kim Featuring T-Pain And Charlie Wilson |
| 34 | Sun Come Up | Jul 2009 | |
| Glasses Malone Featuring Bird, Ross, & T-Pain |
| 35 | Money Round Here | Sep 2009 | |
| C-Ride Featuring T-Pain |
| 36 | Take Your Shirt Off | Nov 2009 | |
| 37 | Body Language | 15 | Nov 2009 | |
| Jesse McCartney Featuring T-Pain |
| 38 | Reverse Cowgirl | Apr 2010 | |
| T-Pain Featuring Young Jeezy |
| 39 | The Manual | Jun 2010 | |
| Travie McCoy Featuring T-Pain And Young Cash |
| 40 | All I Do Is Win | Jul 2010 | |
| DJ Khaled Featuring T-Pain, Ludacris, Snoop Dogg & Rick Ross |
| 41 | My Own Step (Theme From Step Up 3D) | Aug 2010 | |
| Roscoe Dash Featuring T-Pain |
| 42 | Move That Body | Oct 2010 | |
| Nelly Featuring T-Pain And Akon |
| 43 | Rap Song | Nov 2010 | |
| T-Pain Featuring Rick Ross |
| 44 | Black And Yellow REMIX | Feb 2011 | |
| Wiz Khalifa Featuring Juicy J, Snoop Dogg & T-Pain |
| 45 | Hey Baby (Drop It To The Floor) | 5 | Mar 2011 | |
| Pitbull Featuring T-Pain |
| 46 | Boom | Mar 2011 | |
| Snoop Dogg Featuring T-Pain |
| 47 | Welcome To My Hood | Apr 2011 | |
| DJ Khaled Featuring Rick Ross, Plies, Lil Wayne & T-Pain |
| 48 | Best Love Song | 27 | Jun 2011 | |
| T-Pain Featuring Chris Brown |
| 49 | Shake Senora | Jul 2011 | |
| Pitbull Featuring T-Pain & Sean Paul |
| 50 | Booty Wurk (One Cheek At A Time) | Jul 2011 | |
| T-Pain Featuring Joey Galaxy |
| 51 | How To Hate | Sep 2011 | |
| Lil Wayne Featuring T-Pain |
| 52 | The Way You Move | Nov 2011 | |
| DJ Hard Hitta Featuring Ne-Yo, Trey Songz, T-Pain |
| 53 | 5 O'Clock | 8 | Dec 2011 | |
| T-Pain Featuring Wiz Khalifa & Lily Allen |
| 54 | Bang Bang Pow Pow | Dec 2011 | |
| T-Pain Featuring Lil Wayne |
| 55 | 6:00 AM | Mar 2012 | |
| Melanie Fiona Featuring T-Pain |
| 56 | Turn All The Lights On | Apr 2012 | |
| T-Pain Featuring Ne-Yo |
| 57 | Bag Of Money | Sep 2012 | |
| Wale Featuring Rick Ross, Meek Mill And T-Pain |
| 58 | Algo Me Gusta | Oct 2012 | |
| Wisin & Yandel Featuring Chris Brown, T-Pain |
| 59 | Up Down (Do This All Day) | Mar 2014 | |
| T-Pain Featuring B.o.B |
| 60 | Church | Apr 2014 | |
| T-Pain Featuring Teddy Verseti |
| 61 | Red Cup | Oct 2014 | |
| E-40 Featuring T-Pain, Kid Ink & B.o.B |