blue #
= weekly pop chart peak
| 1 | I Get Around | 6 | Sep 1993 |  |
| 2 | Keep Ya Head Up | 25 | Dec 1993 | |
| 3 | Papa'z Song | Apr 1994 | |
| 2Pac With Mopreme |
| 4 | Dear Mama | 21 | May 1995 | |
| 5 | Old School | Jun 1995 | |
| 6 | So Many Tears | Aug 1995 | |
| 7 | Temptations | Oct 1995 | |
| 8 | California Love | 15 | Feb 1996 | |
| 2Pac Featuring Dr. Dre And Roger Troutman |
| 9 | How Do U Want It | 20 | Jul 1996 | |
| 2Pac Featuring K-CI & Jojo |
| 10 | I Ain't Mad At Cha | Nov 1996 | |
| 11 | Runnin' | Apr 1997 | |
| 2Pac, Notorious B.I.G., Radio, Dramacydal & Stretch |
| 12 | Wanted Dead Or Alive | Apr 1997 | |
| 2Pac & Snoop Doggy Dogg |
| 13 | Stop The Gunfight | May 1997 | |
| Trapp - 2Pac - Notorious B.I.G. |
| 14 | Smile | Jul 1997 | |
| Scarface Featuring 2Pac & Johnny P |
| 15 | Thug Luv | Sep 1997 | |
| Bone Thugs-N-Harmony Featuring 2Pac |
| 16 | I Wonder If Heaven Got A Ghetto | Dec 1997 | |
| 17 | Are U Still Down | Jan 1998 | |
| Jon B. with 2Pac |
| 18 | Do For Love | 24 | Apr 1998 | |
| 2Pac Featuring Eric Williams |
| 19 | Happy Home | Nov 1998 | |
| 20 | Changes | 10 | Feb 1999 | |
| 2Pac Featuring Talent |
| 21 | Baby Don't Cry (Keep Ya Head Up II) | Mar 2000 | |
| 2Pac + Outlawz |
| 22 | Until The End Of Time | May 2001 | |
| 2Pac Featuring RL |
| 23 | Letter 2 My Unborn | Nov 2001 | |
| 24 | Thugz Mansion | Dec 2002 | |
| 25 | Still Ballin | Apr 2003 | |
| 2Pac Featuring Trick Daddy |
| 26 | Life Goes On | Sep 2003 | |
| 27 | Runnin (Dying To Live) | Dec 2003 | |
| 2Pac Featuring The Notorious B.I.G. |
| 28 | One Day At A Time | Feb 2004 | |
| 2Pac With Eminem Featuring The Outlawz |
| 29 | Thugs Get Lonely Too | Jan 2005 | |
| 2Pac Featuring Nate Dogg |
| 30 | Ghetto Gospel | Jun 2005 | |
| 2Pac Featuring Elton John |
| 31 | Pac's Life | Feb 2007 | |
| 2Pac Featuring T.I. And Ashanti |
| 32 | Playa Cardz Right | Dec 2008 | |
| Keyshia Cole Featuring 2Pac |