brown #
= weekly rock chart peak
blue #
= pop chart peak
| 51 | Dance With Me | 3 | Dec 2000 |  |
| Debelah Morgan |
| 52 | She Bangs | 3 | Oct 2000 | |
| Ricky Martin |
| 53 | Lucky | 3 | Sep 2000 | |
| Britney Spears |
| 54 | He Wasn't Man Enough | 2 | May 2000 | |
| Toni Braxton |
| 55 | I Wanna Be With You | 4 | Jun 2000 | |
| Mandy Moore |
| 56 | Candy | 2 | Feb 2000 | |
| Mandy Moore |
| 57 | Another Dumb Blonde | 3 | Apr 2000 | |
| Hoku |
| 58 | E.I. | 4 | Dec 2000 | |
| Nelly |
| 59 | Breathe | 3 | Mar 2000 | |
| Faith Hill |
| 60 | Wonderful | 3 | 9 | Sep 2000 | |
| Everclear |
| 61 | Broadway | 30 | 3 | Jun 2000 | |
| Goo Goo Dolls |
| 62 | Teenage Dirtbag | 2 | 3 | Sep 2000 | |
| Wheatus |
| 63 | I Think I'm In Love With You | 6 | Jul 2000 | |
| Jessica Simpson |
| 64 | Thank God I Found You | 2 | Feb 2000 | |
| Mariah Carey Featuring Joe & 98 Degrees |
| 65 | My Baby You | 5 | Oct 2000 | |
| Marc Anthony |
| 66 | Who Let The Dogs Out | 1 | Jul 2000 | |
| Baha Men |
| 67 | Falls Apart | 2 | 4 | Feb 2000 | |
| Sugar Ray |
| 68 | I Need You | 8 | Aug 2000 | |
| LeAnn Rimes |
| 69 | Between Me And You | 6 | Nov 2000 | |
| Ja Rule Featuring Christina Milian |
| 70 | Never Let You Go | 1 | 8 | Feb 2000 | |
| Third Eye Blind |
| 71 | It's True | 8 | Sep 2000 | |
| Backstreet Boys |
| 72 | I Just Wanna Love U (Give It To Me) | 6 | Dec 2000 | |
| Jay-Z |
| 73 | I Wish | 7 | Nov 2000 | |
| R. Kelly |
| 74 | Stronger | 8 | Dec 2000 | |
| Britney Spears |
| 75 | Faded | 11 | Aug 2000 | |
| SoulDecision Featuring Thrust |