blue #
= weekly pop chart peak
| 1 | When In Love | Nov 1991 |  |
| 2 | Poor Georgie | Mar 1992 | |
| 3 | Eyes Are The Soul | Jun 1992 | |
| 4 | Ruffneck | Oct 1993 | |
| 5 | Keep On, Keepin' On | Jun 1996 | |
| MC Lyte Featuring Xscape |
| 6 | Can't Hang | Jun 1996 | |
| Xscape Featuring MC Lyte |
| 7 | Cold Rock A Party | 17 | Feb 1997 | |
| 8 | Come On | Jun 1997 | |
| Billy Lawrence Featuring MC Lyte |
| 9 | Smokin' Me Out | Jul 1997 | |
| Warren G Featuring MC Lyte |
| 10 | I Can't Make A Mistake | Sep 1998 | |
| Mc Lyte |
| 11 | It's All Yours | Dec 1998 | |
| MC Lyte Featuring Gina Thompson |
| 12 | Fighting Temptation | Jul 2004 | |
| Beyonce, Missy Elliott, MC Lyte and Free |
| 13 | What You Won't Do For Love | Sep 2004 | |
| Boyz II Men Featuring MC Lyte |