brown #
= weekly rock chart peak
blue #
= pop chart peak
| 1 | Somebody Told Me | 2 | 19 | Nov 2004 |  |
| 2 | Smile Like You Mean It | 13 | Apr 2005 | |
| 3 | Mr. Brightside | 2 | 3 | May 2005 | |
| 4 | All These Things That I've Done | 20 | Jul 2005 | |
| 5 | Jenny Was A Friend Of Mine | 2005 | |
| 6 | When You Were Young | 1 | 27 | Oct 2006 | |
| 7 | Bones | 13 | Dec 2006 | |
| 8 | A Great Big Sled | Dec 2006 | |
| The Killers Featuring Toni Halliday |
| 9 | Read My Mind | 5 | Apr 2007 | |
| 10 | For Reasons Unknown | Jun 2007 | |
| 11 | Tranquilize | Oct 2007 | |
| The Killers Featuring Lou Reed |
| 12 | Don't Shoot Me Santa | Dec 2007 | |
| 13 | Move Away | 2007 | |
| 14 | Shadowplay | 10 | Jan 2008 | |
| 15 | Joseph, Better You Than Me | Dec 2008 | |
| The Killers Featuring Elton John And Neil Tennant |
| 16 | Human | 5 | 25 | Dec 2008 | |
| 17 | Spaceman | 3 | Feb 2009 | |
| 18 | A Dustland Fairytale | 18 | Jul 2009 | |
| 19 | iHappy Birthday Guadalupe! | Dec 2009 | |
| 20 | The Cowboys' Christmas Ball | Dec 2011 | |
| 21 | Boots | Jan 2012 | |
| 22 | Runaways | 5 | Aug 2012 | |
| 23 | Miss Atomic Bomb | 20 | Dec 2012 | |
| 24 | Here With Me | Jan 2013 | |
| 25 | Just Another Girl | Nov 2013 | |
| 26 | Shot At The Night | 11 | Dec 2013 | |
| 27 | Christmas In L.A. | Dec 2013 | |
| The Killers Featuring Dawes |
| 28 | Joel The Lump Of Coal | Dec 2014 | |
| The Killers Featuring Jimmy Kimmel |